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ergotamine will enhance the amount or impact of tazemetostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
ergotamine, bromocriptine. Both raises toxicity of one other by pharmacodynamic synergism. Stay clear of or Use Alternate Drug. The concomitant usage of bromocriptine with ergot alkaloids may possibly probably cause ergot toxicity; hence The mix really should be avoided.
There isn't any scientific tests on placental transfer or teratogenicity of the combination of ergotamine and caffeine
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Contraindicated (one)itraconazole will raise the level or outcome of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
The United Arab Emirates had said that Spice is surely an unlawful material and possession or intent to offer is really a read more jailable offense.[190]
Monitor Intently (1)ribociclib will increase the degree or impact of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
ergotamine will enhance the stage or influence of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
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elvitegravir/cobicistat/emtricitabine/tenofovir DF improves amounts of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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Contraindicated. Nirmatrelvir/ritonavir is contraindicated with drugs that happen to be extremely dependent on CYP3A for clearance and for which elevated concentrations are connected to serious and/or everyday living-threatening reactions.